Hepatosplenomegaly and polyadenopathy are characteristic features of Letterer-Siwe disease. In patients, there are mastoiditis and otitis media resistant to antibiotics and surgical intervention. Patients have lesions of the limbs, skull bones, pelvic bones, ribs, shoulder blades, and clavicles.

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A sick child practically does not gain weight, his condition deteriorates rapidly, the skin turns pale, appetite decreases and weakness appears. A blood test shows leukopenia or leukocytosis with neutrophilia, hypochromic anemia with aniso- and poikilocytosis, sometimes monocytosis. Myelogram shows polymorphism of elavil marrow cells. The myelogram is characterized by polymorphism of bone marrow cells, sometimes the content of reticulohistiocytic elements is increased.

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FAQs

Abt-Letterer-Siwe disease is a disease of unknown etiology (cause), characterized by reticulohistiocytic proliferation (germination of pathological immune cells) in different organs of the body, which leads to their defeat. As a rule, children of the first or second year of life get sick. Symptoms PrCauses Diagnosis Treatment Complications and consequences Prevention. Symptoms of Abt-Letterer-Siwe disease.

The causes of the disease are unknown. It is assumed that the disease can be caused by bacteria and viruses that affected the pregnant or already born child, as well as ionizing, x-ray radiation.

amitriptyline examination of bones: determines the foci of destruction (destruction), osteoporosis (decrease in bone density). elavil examination of the lungs: reveals areas of swollen lung tissue, small blackouts in the form of nodules. It is also possible to consult an allergist-immunologist, hematologist, dermatologist, pulmonologist.

Analysis of the anamnesis and complaints of the disease (according to the parents): how the disease began - with a sharp rise in body temperature; bleeding vesicles and nodules on the head and body; poor weight gain, loss of appetite; frequent infectious and inflammatory diseases.

General examination: the child is emaciated, pale, lethargic, the skin and mucous membranes are covered with bleeding nodules and scars;

enlarged lymph nodes (neck, head, in the groin), liver and spleen. Complete blood count: anemia is determined (a condition in which a reduced content of red blood cells or an insufficient amount of hemoglobin in them is observed in the bloodstream), lymphocytosis (an increase in immune cells in the blood), thrombocytopenia (a decrease in the number of elavil pills involved in the formation of blood clots in the process of blood clotting to stop bleeding), hyperleukocytosis (a significant increase in the number of leukocytes (white blood cells)).

Treatment of Abt-Letterer-Siwe disease.

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